There are 14 items being released for 2021 Local Comic Shop Day®.
| LCSD 2021 METALLICA 30TH ANNIVERSARY SPECIAL EDITION | Acme Ink |
| LCSD 2021 REGARDING MATTER OF OSWALDS BODY #1 (OF 5) | Boom! Studios |
| LCSD 2021 HOUSE OF SLAUGHTER #1 2ND PTG CARDSTOCK | Boom! Studios |
| LCSD 2021 MAGIC MASTER OF METAL #1 CARDSTOCK GORHAM VARIANT | Boom! Studios |
| LCSD 2021 JOY OPERATIONS #1 (OF 5) | Dark Horse Comics |
| LCSD 2021 DETECTIVE COMICS #1045 SILVER FOIL CARD STOCK VARIANT | DC Comics |
| LCSD 2021 DC VS VAMPIRES #2 (OF 12) SILVER FOIL CARD STOCK VARIANT | DC Comics |
| LCSD 2021 TASK FORCE Z #2 SILVER FOIL CARD STOCK VARIANT | DC Comics |
| LCSD 2021 GRRL SCOUTS STONE GHOST #1 (OF 6) CVR C | Image Comics |
| LCSD 2021 FRIDAY #1 | Image Comics |
| LCSD 2021 WALKING DEAD DLX #27 CVR G ADLARD FOIL VARIANT | Image comics |
| LCSD 2021 VENOM #2 JONBOY MEYERS VARIANT | Marvel Comics |
| LCSD 2021 RADIO APOCALYPSE #1 DLX FOIL FULL ART VARIANT | Vault Comics |
| LCSD 2021 CHUCK D PRESENTS: APOCALYPSE 91 #0 REVOLUTION NEVER SLEEPS | Z2 Comics |
